Showing posts with label Alzheimer's disease. Show all posts
Showing posts with label Alzheimer's disease. Show all posts

Thursday, November 20, 2014

Science Identifies The Catchiest Songs Ever – Did Your Favorite Make The List?

Humans have a deeply rooted love for music and rhythm. For reasons we’ve yet to fully understand, certain types of music bring out the warrior inside of us while other types of music are incredibly soothing. Some songs move us to tears, yet others make us angry. And humans are not alone their capacity to respond to music. There is something about these unnaturally occurring sound patterns that speaks (sings?) to all species capable of sensing the reverberations.

Music can hold great power over us. Songs can change moods, spark memories, or inspire greatness. Some of you may have seen the video of Henry, an unresponsive gentleman in a nursing home, spring back to life after hearing his favorite music. Watch this remarkable episode below as neurologist Oliver Sacks explains the phenomenon.


We are also attuned to how divergent musical tastes can be! Teens rarely like the music that their parents listen to and vice versa. David Hasselhoff has an inexplicable legion of devoted fans in Germany. Michael Bolton somehow scored multiple hits despite piercing millions of eardrums. Some only listen to country, rap, rock, or classical, yet some people have promiscuous ears that love it all. And, let’s admit it, jazz is only fun for the musicians playing it.

Germans love the music of David Hasselhof so much that they've placed an eerily realistic wax statue of The Hoff by the Brandenburg Gate.
John Mellencamp once declared that the world is “polluted” with songs. With an estimated 2-5 billion songs having been written throughout human history, it is pretty remarkable for one to gain widespread popularity. The songs that manage to stand out from the crowd are typically called “earworms” because they are so catchy that you can’t shake them out of your head no matter how hard you try. Some of these tunes dig their talons so deeply into your subconscious that it can be agonizing; for example, here’s a list of infectious songs that were actually used to torture people.

Recently, Dr. John Ashley Burgoyne, who calls himself a computational musicologist, used an online game called “Hooked on Music” as a tool to identify some of the catchiest songs humans have ever concocted. Want to know what they are?

Coming in at number 5 is the ABBA hit, “SOS”:

The fourth catchiest song is “Just Dance” by Lady Gaga:


“Eye of the Tiger” by Survivor, the theme from Rocky III, punches in at #3:


One-hit wonder Lou Bega swings in at #2 with “Mambo No.5”:


And the catchiest song ever…(fake electronic drumroll)…“Wannabe” by the Spice Girls:


It should be noted that Burgoyne’s research relied on an internet game to generate the list of catchy songs, so there is inherent bias among the participants. Other research that employed a different algorithm (or should that be “algorhythm”?) have, perhaps thankfully, revealed different results.

All the fun aside, there is a serious element to researching why catchy songs are so easily remembered. The scientists involved with these types of studies hope that their work will reveal news insights into learning and memory, which could potentially be useful in treating conditions such as Alzheimer’s disease.
Contributed by:  Bill Sullivan
Snowdon CT, & Teie D (2010). Affective responses in tamarins elicited by species-specific music. Biology letters, 6 (1), 30-2 PMID: 19726444

Friday, August 29, 2014

The Friday Five

Highlighting some of the coolest science news we’ve seen lately.

1. Big news in regenerative medicine this week: scientists have grown the first working organ in a lab (a functional thymus was generated from reprogrammed fibroblast cells).


2. It sounds fishy, but zebrafish are helping scientists study potential mechanisms underlying Alzheimer’s disease.

Zebrafish are excellent model systems that help scientists learn about development and disease

3. Another interesting development for Alzheimer’s disease this week. Studies have revealed that infusing the blood of young mice into older mice reverses some of the aging process. Physicians will soon be testing if blood plasma from people under 30 can alleviate the symptoms of Alzheimer’s.

Sorry, Barnabas, but drinking the blood does not work.
4. Better science, better pizza. Scientists set out to “quantify the pizza baking properties and performance of different cheeses”, and the results are described here. Have they found the perfect combination of cheeses? I look forward to trying…


5. Time for a coffee break? No doubt you are familiar with the trademark “coffee ring” that results from spilled coffee, which decorated many of the journal articles I read back when we used to print them out. Based on this study, the video below shows coffee particles in action, forming that characteristic ring.


Science quote of the week:

“Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less” --Marie Curie

Contributed by:  Bill Sullivan
Follow Bill on Twitter: @wjsullivan

Villeda SA, Plambeck KE, Middeldorp J, Castellano JM, Mosher KI, Luo J, Smith LK, Bieri G, Lin K, Berdnik D, Wabl R, Udeochu J, Wheatley EG, Zou B, Simmons DA, Xie XS, Longo FM, & Wyss-Coray T (2014). Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nature medicine, 20 (6), 659-63 PMID: 24793238

Yunker, P., Still, T., Lohr, M., & Yodh, A. (2011). Suppression of the coffee-ring effect by shape-dependent capillary interactions Nature, 476 (7360), 308-311 DOI: 10.1038/nature10344

Ma, X., Balaban, M., Zhang, L., Emanuelsson-Patterson, E., & James, B. (2014). Quantification of Pizza Baking Properties of Different Cheeses, and Their Correlation with Cheese Functionality Journal of Food Science DOI: 10.1111/1750-3841.12540

Bredenkamp, N., Ulyanchenko, S., O’Neill, K., Manley, N., Vaidya, H., & Blackburn, C. (2014). An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts Nature Cell Biology DOI: 10.1038/ncb3023

Friday, August 1, 2014

The Friday Five

Highlighting some of the coolest science news we’ve seen lately.

1. Birds of a feather really do flock together. A recent study finds that you and your friends have similar DNA.


2. Can science help us understand our political differences? Experiments in this new study show that conservatives respond significantly more rapidly to threatening stimuli.



3. You won’t believe the camouflage this gecko is capable of. The only thing better is its name:  the satanic leaf-tailed gecko.



4. Ivan Seah Yu Jun explains Alzheimer’s disease in under 5 minutes in this TED video.




5. So your friends scoff when you rather fist bump than handshake. Now science has justified your action. Fist bumps are the best way to greet someone without adopting their germs.




Science quote of the week:

"All the conditions of happiness are realized in the life of the man of science." –Bertrand Russell 


Contributed by:  Bill Sullivan

Follow Bill on Twitter: @wjsullivan



Hibbing, J., Smith, K., & Alford, J. (2014). Differences in negativity bias underlie variations in political ideology Behavioral and Brain Sciences, 37 (03), 297-307 DOI: 10.1017/S0140525X13001192

Christakis, N., & Fowler, J. (2014). Friendship and natural selection Proceedings of the National Academy of Sciences, 111 (Supplement_3), 10796-10801 DOI: 10.1073/pnas.1400825111